Drug Interactions Of Prevnar 13 Vs Pneumovax 23
In children and adolescents, there is not enough data to know if Prevnar 13 can be given at the same time as Human Papillomavirus Vaccine , Meningococcal Conjugate Vaccine and Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine, Adsorbed .
In adults, no data is available on the administration of Prevnar 13 together with diphtheria toxoid-containing vaccines and other vaccines used in adults 50 years and older.
When Prevnar 13 is administered at the same time as another injectable vaccine, the vaccines should be administered with different syringes and injected at different sites. Prevnar 13 should not be mixed with other vaccines in the same syringe.
Giving Tylenol before Prevnar 13 may reduce the bodys response to the vaccine. Patients who are immunocompromised due to immunosuppressive therapy may not respond optimally to the vaccine.
Patients receiving the shingles vaccine, Zostavax, may have a lower immune response when receiving the vaccine at the same time as Pneumovax 23. The two vaccines should be separated by at least 4 weeks. This should rarely be an issue, though, as Shingrix is now the preferred shingles vaccine. There is limited data regarding other vaccines given at the same time as Pneumovax 23. Consult your healthcare provider for guidance.
Other interactions may occur. Consult your healthcare provider about the possibility of drug or vaccine interactions with Prevnar 13 or Pneumovax 23.
What You Should Know About Pneumonia
Pneumonia is an infection in one or both lungs that typically stems from several kinds of germs, most often bacteria and viruses.
Symptoms can develop gradually or suddenly. They include:
- Chest pain.
- Loss of appetite.
Early detection is often challenging because many people with these symptoms assume they have a cold or the flu.
Its important to also note that the vaccine helps protect against some but not all bacterial pneumonia.
There are dozens of different types of bacterial pneumonia, says Dr. Suri. The vaccine will certainly reduce your risk of the most common bacterial pneumonia.
This Infectious Disease Can Pose A Serious Health Risk For Those Age 65 And Older But Two Vaccines Can Offer Sound Protection
One of the leading health dangers for older adults is pneumonia. It is the most common cause of hospital admissions after childbirth. In fact, adults age 65 and older have a higher risk of death from pneumonia hospitalization than any other reason.
Pneumonia is an infection of the lungs by bacteria, viruses, or other microbes. Most cases are caused by the bacteria Streptococcus pneumoniae, Mycoplasma pneumonia, Chlamydia pneumoniae, Chlamydia psittaci, and Legionella pneumophila. A similar inflammation of the lung, called pneumonitis, can be caused by an inhaled chemical and is more common in people who have had strokes and have difficulty swallowing. A physical exam, chest x-ray, and blood test can confirm a diagnosis.
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The Different Types Of Pneumococcal Vaccine
The type of pneumococcal vaccine you’re given depends on your age and health. There are 2 types.
Pneumococcal conjugate vaccine is used to vaccinate children under 2 years old as part of the NHS vaccination schedule. It’s known by the brand name Prevenar 13.
Children at risk of pneumococcal infections can have the PPV vaccine from the age of 2 years onwards. The PPV vaccine is not very effective in children under the age of 2.
Who Should Not Get The Vaccine
People should not get the vaccine if they have had a life threatening allergic reaction to a previous dose.
Additionally, a person should not undergo vaccination if they have had an allergic reaction to medication containing diphtheria toxoid or an earlier form of the pneumonia vaccination .
Lastly, people who are sick or have allergic reactions to any of the ingredients of the vaccine should talk to a doctor before getting the shot.
A pneumonia shot will not reduce pneumonia. However, it helps prevent invasive pneumococcal diseases, such as meningitis, endocarditis, empyema, and bacteremia, which is when bacteria enter the bloodstream.
Noninvasive pneumococcal disease includes sinusitis.
There are two types of pneumonia shots available. Which type a person gets depends on their age, whether or not they smoke, and the presence of any underlying medical conditions.
The two types are:
- Pneumococcal conjugate vaccine : Healthcare providers recommend this vaccine for young children, people with certain underlying conditions, and some people over the age of 65 years.
- Pneumococcal polysaccharide vaccine : Healthcare providers recommend this vaccine for anyone over 65 years of age, people with certain underlying conditions, and people who smoke.
According to the
- roughly 8 in 10 babies from invasive pneumococcal disease
- 45 in 100 adults 65 years or older against pneumococcal pneumonia
- 75 in 100 adults 65 years or older against invasive pneumococcal disease
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Who Should Get The Pneumonia Vaccine
The Centers for Disease Control and Prevention recommends the pneumococcal vaccine for those who fall into the following groups:
- All babies and children younger than 2 years old.
- All adults 65 years or older.
- Adults 19 through 64 years old who smoke cigarettes.
- Children older than 2 and adults younger than 65 who have certain chronic diseases .
- Those who are at increased risk for certain diseases and those who have impaired immune systems.
The recommendations are sometimes confusing, so its a good idea to talk to your doctor about your questions and concerns, Dr. Suri says.
And dont wait to have that conversation. This is an infection you see year-round, she adds.
What To Do If Your Child Is Unwell After The Vaccine
Its possible that your child may feel unwell after receiving a dose of the pneumococcal vaccine. Should this happen, there are ways to help ease their symptoms.
If your child has a fever, try to keep them cool. You can do this by providing cool liquids for them to drink and ensuring theyre not wearing too many layers.
Tenderness, redness or discoloration, and swelling at the site of the shot can be eased by applying a cool compress. To do this, wet a clean washcloth with cool water and place it gently on the affected area.
Symptoms like fever and pain at the site of the shot may be alleviated using over-the-counter medications like acetaminophen or ibuprofen . Be sure to use the infant formulation and to carefully follow the dosing instructions on the product packaging.
Prior to being approved for use, the safety and effectiveness of all vaccines must be rigorously evaluated in clinical trials. Lets take a look at some of the research into the effectiveness of pneumococcal vaccines.
A evaluated the effectiveness of the PCV13 vaccine in children. It found that:
- The vaccine effectiveness of PCV13 against the 13 pneumococcal strains included in the vaccine was 86 percent.
- The vaccine effectiveness against pneumococcal disease due to any strain of S.pneumoniae was 60.2 percent.
- The effectiveness of PCV13 didnt differ significantly between children with and without underlying health conditions.
The CDC also notes that more than
You shouldnt get the PCV13 vaccine if youre:
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Are You 65 Or Older Get Two Vaccinations Against Pneumonia
- By Gregory Curfman, MD, Assistant Professor of Medicine, Former Editor-in-Chief, Harvard Health Publishing
ARCHIVED CONTENT: As a service to our readers, Harvard Health Publishing provides access to our library of archived content. Please note the date each article was posted or last reviewed. No content on this site, regardless of date, should ever be used as a substitute for direct medical advice from your doctor or other qualified clinician.
If you or a loved one is age 65 or older, getting vaccinated against pneumonia is a good idea so good that the Centers for Disease Control now recommends that everyone in this age group get vaccinated against pneumonia twice.
This new recommendation is based on findings from a large clinical trial called CAPiTA, which were published today in The New England Journal of Medicine.
Streptococcus pneumoniae, sometimes just called pneumococcus, is a common bacterium that can cause serious lung infections like pneumonia. It can also cause invasive infections of the bloodstream, the tissues covering the brain and spinal cord , and other organs and tissues. Older individuals are especially prone to being infected by Pneumococcus, and these infections are often deadly.
The dark spots are pneumonia-causing Streptococcus pneumoniae bacteria isolated from the blood of an infected person.
One caveat is that while PCV13 is effective in preventing pneumonia caused by S. pneumoniae, it does not prevent pneumonia caused by viruses or other bacteria.
Problems That Could Happen After Getting Any Injected Vaccine
- People sometimes faint after a medical procedure, including vaccination. Sitting or lying down for about 15 minutes can help prevent fainting and injuries caused by a fall. Tell your doctor if you or your child:
- Feel dizzy
- Have vision changes
- Have ringing in the ears
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What Are The Main Differences Between Prevnar 13 And Pneumovax 23
Prevnar 13 and Pneumovax 23 are both brand-name vaccines. Prevnar 13 is also known as pneumococcal 13-valent conjugate vaccine injection it protects against 13 different types of pneumococcal bacteria. Prevnar 13 is injected IM .
Pneumovax 23 is also known as pneumococcal vaccine polyvalent injection it protects against 23 types of pneumococcal bacteria. Pneumovax 23 can either be injected IM or SQ .
You will likely receive one vaccine with Prevnar 13, and one vaccine with Pneumovax 23, about one year apart, as an adult.
|Main differences between Prevnar 13 and Pneumovax 23|
|Who typically uses the medication?||Infants, toddlers, children, adults||Less than two years of age who are at increased risk for pneumococcal disease, adults 50 years or older|
I Got A Pneumonia Shot And Then The Pain Began
Last December during a routine physical exam, I received a vaccination to protect against several strains of pneumonia. It hurt, more so than the usual injection. In the days that followed, the pain in my left shoulder worsened. Initially, I dismissed it as typical post-shot soreness. But it didnt go away.
All these months later, it still hurts. My orthopedist says I have subacromial bursitis, which is chronic inflammation and excess fluid buildup in the bursa separating the acromion bone at the top of the shoulder from the rotator cuff.
Im convinced this occurred because the nurse injected the vaccine too high on my arm. I had no symptoms before the shot, and pain has persisted since. The needle probably entered the top third of the deltoid muscle which forms the rounded contours of the shoulder and probably went into the bursa or the rotator cuff, instead of lower down, into the middle part of the muscle, missing the bursa and rotator cuff entirely. I say probably because I wasnt watching. Like many, I avert my eyes at the sight of an approaching needle.
A third of the patients needed surgery, some of them twice.
There is no single way to treat shoulder injuries, regardless of how they occur. Treatments that work for some may not work for others.
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What Are The Most Common Side Effects Of Pneumovax 23 And Prevnar 13
Side effects with pneumococcal vaccines are usually mild and go away on their own within a few days.
Common side effects of Prevnar 13 include:
Injection site pain
Common side effects of Pneumovax 23 include:
Injection site pain
Be sure to talk with your doctor if you experience any of these symptoms for a prolonged period of time.
Path To Improved Health
Pneumococcal vaccines can protect you against getting pneumonia, which is contagious and spreads from close, person-to-person contact. Pneumonia is an infection of the lungs and can lead to many symptoms, including:
- chest pains
- bringing up mucus when you cough
For seniors, pneumonia can be very serious and life-threatening. This is especially true if you have a chronic condition, such as diabetes or COPD. Pneumonia can also develop after youve had a case of the flu or a respiratory virus such as COVID-19. It is extremely important to stay current on flu shots each year in addition to your pneumococcal vaccines.
While PPSV23 and PCV13 do not protect against all types of pneumonia, they can make it less likely that you will experience severe and possibly life-threatening complications from the illness.
The American Academy of Family Physicians recommends that seniors who have not had either pneumococcal vaccine should get a dose of PCV13 first, and then a dose of PPSV23 6-12 months later. The vaccines cannot be given at the same time. If you have recently had a dose of PPSV23, your doctor will wait at least one year to give you PCV13.
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Are Prevnar 13 And Pneumovax 23 The Same
Not quite. They both protect against pneumococcal bacteria. Prevnar 13 protects against 13 types of bacteria, and Pneumovax 23 protects against 23 types of bacteria. Prevnar 13 is given in the muscle , while Pneumovax 23 can be given either in the muscle or under the skin . Most adults over 65 will receive one dose of each vaccine, one year apart.
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Adults At High Risk Of Ipd
Adults with immunocompromising conditions resulting in high risk of IPD, except HSCT, should receive 1 dose of Pneu-C-13 vaccine followed at least 8 weeks later by 1 dose of Pneu-P-23 vaccine, if not previously received. The dose of Pneu-C-13 vaccine should be administered at least 1 year after any previous dose of Pneu-P-23 vaccine. Refer to Immunocompromised persons for information about immunization of HSCT recipients.
Immunocompetent adults with conditions or lifestyle factors resulting in high risk of IPD should receive 1 dose of Pneu-P-23 vaccine, if not previously received. One dose of Pneu-P-23 vaccine is also recommended for all adults who are residents of long-term care facilities and should be considered for individuals who use illicit drugs.
Some experts also suggest a dose of Pneu-C-13 vaccine, followed by Pneu-P-23 vaccine, for immunocompetent adults with conditions resulting in high risk of IPD as this may theoretically improve antibody response and immunologic memory. However, Pneu-P-23 vaccine is the vaccine of choice for these individuals, and if only one vaccine can be provided, it should be Pneu-P-23 vaccine, because of the greater number of serotypes included in the vaccine.
Adults at highest risk of IPD should also receive 1 booster dose of Pneu-P-23 vaccine refer to Booster doses and re-immunization.
Table 4 – provides recommended schedules for adult immunization with pneumococcal vaccines.
Should Adults Over 65 Get Prevnar 13
PCV13 is still a safe and effective vaccine, especially if you have medical conditions or live in a place with high risk of exposure to pneumococcal strains, such as a nursing home or long-term care facility. Doctors and their patients need to consider both the exposure risk and personal risks for each patient to decide whether Prevnar 13 is necessary. If you have questions about either vaccine, talk to your doctor or pharmacist.
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According to the CDC, only about 70% of adults aged 65 and older ever receive a pneumococcal vaccination, either PCV13 or PPSV23. Hopefully, the new recommendations will encourage more people to get vaccinated since healthy adults now only need a single dose rather than two doses.
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What If You Never Got Prevnar 13 As A Child
Lets say you never got a vaccine for pneumococcal bacteria when you were little . Most of you will just wait until you turn 65 years old, at which time, youll get Prevnar 13 followed by Pneumovax 23 at least 1 year later.
In certain cases, the timing may be different. Your provider will be able to advise you based on your specific situation.
What If It Is Not Clear What A Person’s Vaccination History Is
When indicated, vaccines should be administered to patients with unknown vaccination status. All residents of nursing homes and other long-term care facilities should have their vaccination status assessed and documented.
How long must a person wait to receive other vaccinations?
Inactivated influenza vaccine and tetanusvaccines may be given at the same time as or at any time before or after a dose of pneumococcus vaccine. There are no requirements to wait between the doses of these or any other inactivated vaccines.
Vaccination of children recommended
In July 2000, the American Academy of Pediatrics and the CDC jointly recommended childhood pneumococcal immunization, since pneumococcal infections are the most common invasive bacterial infections in children in the United States.
“The pneumococcal conjugate vaccine, PCV13 or Prevnar 13, is currently recommended for all children younger than 5 years of age, all adults 65 years or older, and persons 6 through 64 years of age with certain medical conditions,” according to the 2014 AAP/CDC guidelines. “Pneumovax is a 23-valent pneumococcal polysaccharide vaccine that is currently recommended for use in all adults 65 years of age or older and for persons who are 2 years and older and at high risk for pneumococcal disease . PPSV23 is also recommended for use in adults 19 through 64 years of age who smoke cigarettes or who have asthma.”
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